Which is better for Anxiety, Etizolam or Clonazepam?

There are various medications out there that work well for the treatment of anxiety. However, narrowing down which works best for you can be quite challenging. For example, many individuals tend to get a bit confused between Etizolam and Clonazepam, as many claims that both have the same effects on those with anxiety. However, there is a slight difference. The results of both vary depending on the individual, and a number of factors are related to the variation of the effect. The following factors play a vital role in how each medication affects you:

  • Your body weight
  • Any pre-existing medical conditions
  • Medications that you are currently taking


Etizolam is mainly used to treat insomnia and anxiety disorders. It is one of the most common treatments for anxiety disorders, as its anti-anxiety properties are quite beneficial. However, the hypnotic effects are subpar. In fact, in higher doses of Etizolam, one can experience side effects like hypnosis, sedation, complete loss of motor control, and other common side effects associated with sleeping pills. Furthermore, Etizolam can not be combined with any other medications, which can cause various complications as it can result in severe contraindications.


Similarly, Clonazepam is primarily used to treat anxiety and panic disorders. It is also used to treat sleeping disorders but is often combined with other medications for the best results. Clonazepam works by upping the levels of a calming chemical found in the brain. This particular function singlehandedly relieves anxiety and stops seizures along with fits. It is also great for relaxing tense muscles. The prevalent side effect is excessive drowsiness. Clonazepam may be prescribed to treat different anxiety disorders, including social anxiety disorder, panic disorder, as well as generalized anxiety disorder.

Difference between Etizolam and Clonazepam

Clonazepam is quick acting and lasts for a more extended amount of time as compared to Etizolam. It is vital to note that since it acts quite rapidly, you can take the medication whenever it is required. Taking the drug every day is not recommended as it can lead to dependence. Clonazepam has a longer duration of action, which is nearly up to 12 hours.

On the other hand, Etizolam only lasts for 6 to 8 hours. While Etizolam has a similar half-life, and it gets reduced to half of the original concentration in your blood after six hours pass. However, Etizolam's effects peak around three hours in and start to fade slowly after that. Clonazepam's half-life is 30 to 40 hours, which means the drug remains in the body for about three days. Both of the medications can cause next-day drowsiness, though.

The Takeaway

Some people prefer Clonazepam over Etizolam due to its specific properties, like it is more long-lasting. However, others prefer Etizolam as they prefer their medications not to last as long. It all comes down to personal preference. In general, if you are looking for a quick-acting, long-lasting treatment for your anxiety disorder, it is better to go with Clonazepam.